The mission of the Department of Clinical Pharmacology and Therapeutics of Seoul National University Hospital (SNUCPT) is "As one of the world's leading groups for innovative research, education/training, and clinical pharmacology practice, will maximize the effectiveness of medicines by creating, applying and promoting integrated information and knowledge for personalized optimal pharmacotherapy. These efforts will contribute to a healthier and happier life for people around the world.". Based on the mission, the department conducts various research, education, treatment, and treatment support activities on clinical pharmacology, clinical trials, and optimal pharmacotherapy.

In June 1988, SNUCPT started as a Clinical Pharmacology Task Force under the Board of Pharmacy Affairs and organized as an official institution of the Supporting Services which is 'Clinical Pharmacology Unit' in June 1994. As a major member of the Clinical Trials Center, established in 1996, it has been gradually expanding its role. Conducting not only pharmacotherapeutic consultations regarding therapeutic drug monitoring (TDM) but also, early phase clinical trials, consultation of new drug clinical development and clinical drug research, pharmacokinetic /pharmacodynamic analysis, clinical trial simulation, and clinical trials expert training. In addition, it was designated as a Regional Clinical Trial Center by Ministry of Health and Welfare. In December 2007, the unit grew to 'Department of Clinical Pharmacology and Therapeutics' since the role of a clinical pharmacologist, the expert of clinical trials and personalized optimal pharmacotherapy, has been increased in the hospital. Moreover, the College of Medicine established 'Department of Clinical Pharmacology and Therapeutics' in March 2012.

Currently, more than 40 clinical projects related to personalized optimal pharmacotherapy are carried out each year independently or in collaboration with other departments, and approximately 10,000 cases of TDM consultation and 700 cases of consultation of personalized optimal pharmacotherapy are conducted each year. The SNUCPT’s clinical activities are focused on translational research and practice and encompasses the fields of basic medical science (clinical pharmacokinetics, pharmacodynamics, genetics, pharmacology and biochemistry, biostatistics, analytical chemistry, pharmacogenomics, metabolomics, etc.) and clinical medical science (clinical application of personalized optimal pharmacotherapy). Specifically, the members of SNUCPT performs consultation on personalized optimal pharmacotherapy based on various patient characteristics such as pharmacokinetics, pharmacodynamics, disease status, drug interaction, genetic diversity. Also, the members of SNUCPT are generating evidences for those clinical activities by various research activities (e.g., clinical trials, pharmacokinetics/pharmacodynamics modeling and simulation). In addition, SNUCPT has built a foundation for new drug development and personalized pharmacotherapy by training and educating professional experts in drug clinical development and pharmacotherapy field through the clinical pharmacology specialist training program.

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